DCCC.

Open science, one scan at a time.

中文 GitHub

DEEP CASCADED CEREBRAL CALCULATOR

A clearer picture
of brain PET.

For clinicians, researchers,
and AI agents.

MRI-free · Centiloid · CenTauR · SUVr

THREE TOOLS. YOUR WAY IN.

dcccpy

PYTHON ↗

Python tools for PET neuroimaging research.

pip install dcccpy

less preparation, more exploration.

Loading brain…
50 CL
050100 CL
Illustrative PET uptake, interpolated between different participants. Not measured scans or disease progression. Details are available in About the illustration.
View acknowledgements
↑ DCCC

DCCC / ACKNOWLEDGEMENTS

Acknowledgements.

Thanks to the clinicians, researchers and community members who contributed data, testing and feedback to DCCC.

From the community

Research data

ADNI ↗

Alzheimer’s Disease Neuroimaging Initiative

Research data used in the Radiology study. We thank the investigators and study participants.

Study team & credits ↗

AIBL ↗

Australian Imaging, Biomarkers and Lifestyle Study of Ageing

Research data used in the Radiology study. We thank the AIBL researchers and study participants.

Study team & credits ↗

BEHIND THE ILLUSTRATION

Real PET. A shared surface.

Eleven native-space PET images were normalized with DCCC, referenced to whole-cerebellum uptake, and projected onto the Colin27 pial surface. An affine T1-to-T1 registration aligns the template spaces. Cortical MIP takes the maximum of 12 samples along each inward surface normal, 0.5–6 mm beneath the pial surface, restricted to gray-matter-supported locations.

The continuous slider uses a simplified illustrative 0–100 CL scale, blending the PET examples selected for nominal 10-CL intervals. Example values are approximate; the actual supplied CL values remain in the provenance. Intermediate frames are visual interpolations, not measured scans. These are different participants, not disease progression. Low uptake is transparent over the neutral anatomy. A red pigment layer appears smoothly between 1.1 and 1.75 SUVr. These are display settings, not clinical thresholds or a validated cross-tracer calibration for PiB and AV45.

Source CL values are retained without recalculation, including 82.82 and 112.57 CL for the nominal 90/100 examples. This illustration used the explicitly selected local DCCCcore 4.6.1-alpha runtime. Original PET images and processing records remain local.

Surface provenance ↗ · Colin27 anatomy ↗ · Credits ↗